TANDOSPIRONE

Manufacturers supply cost-effective and customizable TANDOSPIRONE 87760-53-0 We provide high quality TANDOSPIRONE (CAS 87760-53-0), at a very affordable prices to our customers.

1.What is the TANDOSPIRONE ?

Tandospirone is another 5-HT1A receptor agonist under development by Sumitomo Pharmaceutical Co., Ltd., in Japan and Pfizer in the United States. Results of phase II and phase III clinical trials show that tandospirone is effective for the treatment of anxiety neurosis. Significant improvement is also observed in patients with psychosomatic disease, phobia, and depersonalization (Murasaki 1995). The results have shown that initial treatment should be started at 30 mg daily, and the dose should be increased up to 60 mg daily according to symptoms (Murasaki 1995). A double-blind comparative study with diazepam revealed that tandospirone tends to be superior to diazepam in patients with depressive neurosis, whereas diazepam may be more effective than tandospirone in severely ill patients (Murasaki et al. 1992).

Tandospirone is a 5HT1A receptor partial agonist. Studies indicate that tandospirone significantly reduces haloperidol-induced bradykinesia in a dose dependent manner. The potency of Tandospirone is equal to that of buspirone and approximate one-half that of diazepam. The potency of Tandospirone at dopamine antagonistic action is less than 1/4 that of buspirone.

2.What is the CAS number for TANDOSPIRONE ?

The CAS number of TANDOSPIRONE is 87760-53-0.

More information of TANDOSPIRONE 87760-53-0 are:

3.What is the molecular formula of TANDOSPIRONE ?

The chemical formula of?TANDOSPIRONE is C21H29N5O2 which containing 21 Carbon atoms,29 Hydrogen atoms,5 Nitrogen atoms and 2 Oxygen atoms,and the molecular weight, and the molecular weight of TANDOSPIRONE is 383.494

4.What is TANDOSPIRONE(87760-53-0)used for?

Tandospirone is another 5-HT1A receptor agonist under development by Sumitomo Pharmaceutical Co., Ltd., in Japan and Pfizer in the United States. Results of phase II and phase III clinical trials show that tandospirone is effective for the treatment of anxiety neurosis. Significant improvement is also observed in patients with psychosomatic disease, phobia, and depersonalization (Murasaki 1995). The results have shown that initial treatment should be started at 30 mg daily, and the dose should be increased up to 60 mg daily according to symptoms (Murasaki 1995). A double-blind comparative study with diazepam revealed that tandospirone tends to be superior to diazepam in patients with depressive neurosis, whereas diazepam may be more effective than tandospirone in severely ill patients (Murasaki et al. 1992).

InChI:InChI=1/C21H29N5O2/c27-19-17-15-4-5-16(14-15)18(17)20(28)26(19)9-2-1-8-24-10-12-25(13-11-24)21-22-6-3-7-23-21/h3,6-7,15-18H,1-2,4-5,8-14H2/t15-,16+,17+,18-

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5.Manufacturers supply cost-effective and customizable TANDOSPIRONE 87760-53-0

Hebei Road biotechnology co., LTD is a quality supplier of TANDOSPIRONE. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on TANDOSPIRONE 87760-53-0.