L-A-HYDROXYGLUTARIC ACID DISODIUM)
- Name: L-A-HYDROXYGLUTARIC ACID DISODIUM)
- CAS: 63512-50-5
- Purity: 99%
Details
Quality products?make an important contribution to long-term revenue and profitability. High Quality Chinese Manufacturer supply 63512-50-5 L-A-HYDROXYGLUTARIC ACID DISODIUM)
1.What is the L-A-HYDROXYGLUTARIC ACID DISODIUM) ?
L-α-Hydroxyglutaric acid disodium salt is suitable for use in collection buffer for increased recovery of hypoxia-inducible factor-1 α (HIF-1α), a marker of hypoxia in human tumors. It is also suitable for the radiolabeled 5mC-5hmC conversion assay to study the effect of 2-HG on the TET family of methyl hydroxylases.
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56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6
L-glutamic acid
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40951-21-1,55714-86-8,63512-50-5,103404-90-6
(S)-2-hydroxypentanedioic acid, disodium salt
| Conditions | Yield |
|---|---|
|
L-glutamic acid;
With
potassium nitrite; sulfuric acid;
In
water;
at -10 ℃;
With
sodium hydroxide;
Further stages.;
|
62%
|
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-
21461-84-7
(2S)-tetrahydro-5-oxofuran-2-carboxylic acid
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-
40951-21-1,55714-86-8,63512-50-5,103404-90-6
(S)-2-hydroxypentanedioic acid, disodium salt
| Conditions | Yield |
|---|---|
|
With
sodium hydroxide;
In
water;
at 25 ℃;
for 2h;
pH=10;
|
31.43%
|
2.What is the CAS number for L-A-HYDROXYGLUTARIC ACID DISODIUM) ?
The CAS number of L-A-HYDROXYGLUTARIC ACID DISODIUM) is 63512-50-5.
More information of L-A-HYDROXYGLUTARIC ACID DISODIUM) 63512-50-5 are:
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CAS?Number |
63512-50-5 |
|
Melting Point |
>300°C |
|
PSA |
100.49000 |
|
LogP |
-3.37270 |
3.What are another words for L-A-HYDROXYGLUTARIC ACID DISODIUM) ?
Synonyms?for?L-A-HYDROXYGLUTARIC ACID DISODIUM) 63512-50-5:L-alpha-Hydroxyglutaric acid, disodium salt;(S)-2-Hydroxypentanedioic acid;L-α-Hydroxyglutaric acid disodium salt;(2S)-2-Hydroxyglutaric acid disodium salt;Pentanedioic acid, 2-hydroxy-, disodium salt, (S)- (9CI);
4.What is the molecular formula of L-A-HYDROXYGLUTARIC ACID DISODIUM)?
The chemical formula of ?L-A-HYDROXYGLUTARIC ACID DISODIUM) is?C5 H6 O5 *2Na which containing 5 Carbon atoms,6 Hydrogen atoms,1 Oxygen atoms and 1 Sodium atoms,and the molecular weight of??L-A-HYDROXYGLUTARIC ACID DISODIUM)?is 192.079.
5.What is L-A-HYDROXYGLUTARIC ACID DISODIUM) (63512-50-5) used for?
L-α-Hydroxyglutaric acid (L-2-HG) is an α-hydroxy acid. It is metabolized to 2-oxoglutarate (α-ketoglutarate) by L-2-hydroxyglutarate dehydrogenase, and mutations in this enzyme lead to 2-hydroxyglutaric aciduria, a neurometabolic disorder characterized by increased L-2-HG levels. L-2-HG is structurally similar to α-ketoglutarate and competitively inhibits α-ketoglutarate-dependent dioxygenases, including several involved in histone lysine and DNA demethylation.
InChI:InChI=1/C5H8O5.2Na/c6-3(5(9)10)1-2-4(7)8;;/h3,6H,1-2H2,(H,7,8)(H,9,10);;/q;2*+1
Relevant articles related to L-A-HYDROXYGLUTARIC ACID DISODIUM):
|
Article |
Source |
|
Pteridines Part CXVIII. Methanopterin, chemical approach and partial synthesis |
Heizmann, Gerhard,Pfleiderer, Wolfgang , p. 1856 - 1873 (2008/03/12) |
6.Buy L-A-HYDROXYGLUTARIC ACID DISODIUM) with the best price .
Hebei Road biotechnology co., LTD is a quality supplier of L-A-HYDROXYGLUTARIC ACID DISODIUM). Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on L-A-HYDROXYGLUTARIC ACID DISODIUM) 63512-50-5.
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